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Blood Culture-Negative Infective Endocarditis (BCNIE) Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... cultures remain negative ... antimicrobials, clinical ... but important causes ... differential #workup #infectiousdiseases
Microorganisms Responsible for Infective Endocarditis Native valves: - Streptococcus viridans - Enterococci - Other streptococci
epidermidis - Gram-negative ... ) - Culture negative ... Enterococci - Gram-negative ... streptococci - Culture negative ... #Differential #InfectiousDiseases
HACEK is the acronym commonly used to describe and help doctors to remember a group of
fastidious Gram-negative ... which can also cause ... endocarditis is caused ... endocarditis is caused ... #Diagnosis #InfectiousDiseases
Causes of Relative Bradycardia - Note the propensity for intracellular organisms. Infectious: Legionella, Psittacosis, Q fever, Typhoid
Causes of Relative ... Drug fever #relative ... #bradycardia #Causes ... differential #diagnosis #infectiousdiseases
Causes of blood culture negative infective endocarditis Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
Causes of blood ... culture negative ... febrilepodcast] #BCNIE #Causes ... #culture #negative ... #Endocarditis #InfectiousDiseases
Endocarditis Algorithm - Infective vs Noninfective Causes Noninfective: • Malignancy • Autoimmune disease • Systemic infection Native Valve
vs Noninfective Causes ... HACEK • Culture-negative ... epidermidis • Gram-negative ... Enterococcus • Gram-negative ... #Noninfective #Causes
Transplant Infections Timeline Pre-transplant: • Common bacteria (endogenous): Staphylococci (skin), Gram-negative bacilli (gut) • Viruses: HSV (reactivation) Engraftment:
Staphylococci (skin), Gram-negative ... Staphylococci (skin), Gram-negative ... differential #diagnosis #causes ... #infectiousdiseases
Table 3. Suggested Empiric Treatment Options for Clinically Suspected Ventilator-Associated Pneumonia in Units Where Empiric Methicillin-Resistant
Treatment Options for Clinically ... Antipseudomonal/Gram-Negative ... Appropriate #Management #InfectiousDiseases
Causes of Culture Negative Abscess - Differential Diagnosis Framework Consider prior antibiotics as a cause of a
Causes of Culture ... Negative Abscess ... antibiotics as a cause ... of a negative culture ... Differential #Diagnosis #InfectiousDiseases
USMLE Epidemiology and Biostatistics Summary Meta-Analysis: pools data from several studies (greater power), limited by quality/bias of
individual studies Clinical ... diseases, describe clinical ... 100%, then all negative ... proportion of negative ... that are true negatives
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