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Table 3. Suggested Empiric Treatment Options for Clinically Suspected Ventilator-Associated Pneumonia in Units Where Empiric Methicillin-Resistant
Treatment Options for Clinically ... Antipseudomonal/Gram-Negative ... Appropriate #Management #InfectiousDiseases
CAPD-associated peritonitis (Continuous Ambulatory Peritoneal Dialysis) - 5 Things To Know
Diagnosis (Two of the following):
(1) Clinical
following): (1) Clinical ... • 15-35% Gram negative ... Others • Culture negative ... Diagnosis #Management #InfectiousDiseases
Tuberculosis Testing

LATENT TB
• LTBI is diagnosed when an asymptomatic patient has a positive TST or IGRA
result with no clinical ... testing (TST) False-negative ... because false-negative ... sample = 95% • A negative ... LatentTB #ActiveTB #InfectiousDiseases
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... cultures remain negative ... antimicrobials, clinical ... #BloodCulture #Negative ... differential #workup #infectiousdiseases
"Scrotal Pain + Uganda:Almost never see it in the developed world unless you are like this
infectious despite negative ... Emergency Medicine #Clinical ... POCUS #Urology #InfectiousDiseases
Microorganisms Responsible for Infective Endocarditis

Native valves:
 - Streptococcus viridans 
 - Enterococci 
 - Other streptococci
epidermidis - Gram-negative ... ) - Culture negative ... Enterococci - Gram-negative ... streptococci - Culture negative ... #Differential #InfectiousDiseases
Important Biostatistics and Epidemiology Equations

Sensitivity = TP / (TP + FN) = true positives / disease
FP + TN) = true negatives ... all positives Negative ... FN + TN) = true negatives ... / all negatives ... Specificity) Negative
Endocarditis Algorithm - Infective vs Noninfective Causes
Noninfective:
 • Malignancy
 • Autoimmune disease
 • Systemic infection
Native Valve
Systemic infection Native ... Staphylococcus lugdunensis Native ... HACEK • Culture-negative ... epidermidis • Gram-negative ... Enterococcus • Gram-negative
Transplant Infections Timeline
Pre-transplant:
 • Common bacteria (endogenous): Staphylococci (skin), Gram-negative bacilli (gut)
 • Viruses: HSV (reactivation)
Engraftment:
Staphylococci (skin), Gram-negative ... Staphylococci (skin), Gram-negative ... diagnosis #causes #infectiousdiseases
Causes of Relative Bradycardia - Note the propensity for intracellular organisms.
Infectious: 
Legionella, Psittacosis, Q fever, Typhoid
Causes of Relative ... Drug fever #relative ... differential #diagnosis #infectiousdiseases