71 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Positive in 60-80% of cases ... pANCA anti-MPO - Negative ... #SLE #lupus #Systemic ... #Summary #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... autoantibodies that will cause ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis #management
Tularemia - Diagnosis and Management Summary
Francisella tularensis - Aerobic fastidious gram-negative Coccobacillus - Zoonotic Infection
 •
Diagnosis and Management ... fastidious gram-negative ... • Typhoidal: Systemic ... conditions Diagnosis: Serology ... #treatment #infectiousdiseases
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm
Congenital
Medications
 • Anticonvulsants
 • Antibiotics
 • Antithyroid
 • Antihypertensive
Causes of Isolated ... Bacteria • Gram Negative ... Destruction • Systemic ... Diagnosis #Algorithm #Causes ... #Hematology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
FLAGS - In all cases ... guidelines General - Systemic ... splenomegaly, abnormal neurology ... , back pain Haematology ... cell disease Rheumatology
Hepatitis B Virus Serology and Interpretation
HBsAg - Anti-HBs - Anti-HBc - HBeAg - Anti-HBe
 - Acute
Hepatitis B Virus Serology ... level) or HBeAg-negative ... (about 10% of cases ... HepatitisB #HBV #Serology ... diagnosis #laboratory #hepatology
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Diagnosis and Management ... Summary Pathophysiology ... - Erosions and crusts ... Systemic glucorticoids ... #dermatology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Pauci-immune mediated (Negative ... diagnosis #algorithm #rheumatology
Differentiating NBTE from Infective Endocarditis
No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
features: Fever -, Systemic ... : Serial negative ... features: Fever +, Systemic ... : + (Negative blood ... in up to 30% of cases
Schizophrenia: Pathogenesis and Symptoms
Increased dopaminergic transmission in mesolimbic projection
-> Dopaminergic neurons here project into the limbic
into the limbic system ... is thought to cause ... is thought to cause ... Negative Symptoms ... Schizophrenia #pathophysiology