114 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Positive in 60-80% of cases ... pANCA anti-MPO - Negative ... life-threatening • Treatment ... #Summary #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... autoantibodies that will cause ... Puncture, EEG Treatment ... cerebritis #diagnosis #management ... #treatment
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... pANCA anti-MPO - Negative ... life-threatening • Treatment ... Usual therapeutic management ... #diagnosis #management
Table 3. Suggested Empiric Treatment Options for Clinically Suspected Ventilator-Associated Pneumonia in Units Where Empiric Methicillin-Resistant
Suggested Empiric Treatment ... Antipseudomonal/Gram-Negative ... Are Appropriate #Management ... #InfectiousDiseases
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Post-strep GN, Lupus ... Pauci-immune mediated (Negative ... diagnosis #algorithm #rheumatology
Here is a quick guide on the common direct-acting antivirals (DAAs) for chronic hepatitis C virus
Antivirals #table #treatment ... #medications #infectiousdisease ... #hepatology #HepC ... #HepatitisC #Management
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm
Congenital
Medications
 • Anticonvulsants
 • Antibiotics
 • Antithyroid
 • Antihypertensive
Causes of Isolated ... Bacteria • Gram Negative ... Destruction • Systemic Lupus ... Diagnosis #Algorithm #Causes ... #Hematology
Cyanide Toxicity 
Treatment:
1) Hydroxocobalamin + Cyanide = Cyanocobalamin (nontoxic) 
   or 
2) Amyl nitrite
Cyanide Toxicity Treatment ... Amyl nitrite - causes ... Toxicity #Toxicology #Pathophysiology ... #Management #Treatment
Psittacosis 
Pathogen: Chlamydia psittaci - obligate intracellular gram negative
Transmission:
 • Birds are the primary reservoir
 •
intracellular gram negative ... danger of aerosol) Treatment ... first line of treatment ... microbiology #diagnosis #management ... #treatment #infectiousdiseases
Causes of Aplastic Anemia

#Aplastic #Anemia #Causes #Pathophysiology #Pathology #Treatment #Management #Differential
Causes of Aplastic ... Aplastic #Anemia #Causes ... #Pathophysiology ... #Pathology #Treatment ... #Management #Differential