20 results
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
Infective Endocarditis ... but important causes ... exists Infectious Diseases ... #differential #workup ... #infectiousdiseases
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Cryoglobulinemia, Endocarditis ... involvement: Anti-GBM Disease ... Pauci-immune mediated (Negative
Differentiating NBTE from Infective Endocarditis
No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
: Serial negative ... Frequent false-negative ... : + (Negative blood ... in up to 30% of cases ... - Infectious Diseases
Tularemia - Diagnosis and Management Summary
Francisella tularensis - Aerobic fastidious gram-negative Coccobacillus - Zoonotic Infection
 •
fastidious gram-negative ... conditions Diagnosis: Serology ... Culture & GS, PCR Treatment ... : • Severe Disease ... #infectiousdiseases
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
• Immunologic Workup ... Positive in 60-80% of cases ... pANCA anti-MPO - Negative ... life-threatening • Treatment ... Evolution: Chronic disease
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup ... patients with a negative ... Renal parenchymal disease ... Neurologic disorders ... #Hypertension #Workup
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
aureus, Coagulase-negative ... Septic emboli cause ... hematuria, + RF Treatment ... Treat underlying cause ... Diagnosis #cardiology #infectiousdiseases
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... Discontinuation of causal ... • Immunologic Workup ... pANCA anti-MPO - Negative ... Evolution: Chronic disease
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Cerebrovascular Disease ... , PRES Pathophysiology ... autoantibodies that will cause ... Puncture, EEG Treatment ... Erythematosus #SLE #CNS #neurology
Invasive Aspergillus (IA) - Diagnosis and Management
Aspergillus is ubiquitous in nature. Most invasive infections are caused
infections are caused ... Endophthalmitis, Endocarditis ... this morphology Treatment ... vori Infectious Diseases ... #fungal #infectiousdiseases