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diagnosis infections differential management associated betadglucan biomarkers causes dementia disorder galactomannan hand hematology ia invasive lung mycoses neurocognitive neurology pulmonary
Transplant Infections Timeline Pre-transplant: • Common bacteria (endogenous): Staphylococci (skin), Gram-negative bacilli (gut) • Viruses: HSV (reactivation) Engraftment:
Staphylococci (skin), Gram-negative ... Staphylococci (skin), Gram-negative ... (mucosa), Aspergillus ... : Aspergillus spp ... diagnosis #causes #infectiousdiseases
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
Coccidioides - Negative ... products - IV ... Cellulose filters for IV ... Cryptococcus - Negative ... Galactomannan #diagnosis #comparison
Invasive Aspergillus (IA) - Diagnosis and Management Aspergillus is ubiquitous in nature. Most invasive infections are caused
Invasive Aspergillus ... SOT, Advanced HIV ... /AIDS, CGD) Clinical ... Management #treatment #fungal ... #infectiousdiseases
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
blood donor • Pathophysiology ... : 2 hit mechanism ... to explain symptoms ... transfusion • Pathophysiology ... hematology #diagnosis #comparison
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
impairment • HIV ... dementia Pathophysiology ... • Depressive symptoms ... sequences with relative ... disorder #dementia #AIDS
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Pseudomonas FUNGAL ... since cART) Aspergillus ... Constitutional symptoms ... #AIDS #pulmonary ... differential #diagnosis #infectiousdiseases
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
yeast • At risk: AIDS ... ASPERGILLOSIS • Aspergillus ... Aspergillosis Pathophysiology ... ) #Mycoses #InfectiousDiseases ... #Fungal #Diagnosis
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