19 results
Causes of blood culture negative infective endocarditis

Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
culture negative ... infective endocarditis ... #culture #negative ... #Endocarditis # ... InfectiousDiseases #Microbiology
My Patient with Infective Endocarditis (IE) Has Negative Blood Cultures
 - Did they receive antibiotics prior
with Infective Endocarditis ... (IE) Has Negative ... therapy - Number one cause ... of culture negative ... #Infective #Endocarditis
Endocarditis Algorithm - Infective vs Noninfective Causes
Noninfective:
 • Malignancy
 • Autoimmune disease
 • Systemic infection
Native Valve
Endocarditis Algorithm ... vs Noninfective Causes ... • HACEK • Culture-negative ... amzn.to/2LmUODZ #Endocarditis ... #Noninfective #Causes
Epidemiological Clues That May be Helpful in Defining the Etiological Diagnosis of Culture-Negative Endocarditis

#Endocarditis #Bacteria #Differential
Epidemiological Clues ... Etiological Diagnosis of Culture-Negative ... Endocarditis ... #Endocarditis #Bacteria ... Microorganisms #Clues
Streptocccus Pneumoniae
Microbiology: Gram Positive, Alpha-hemolytic, Catalase Negative
Epidemiology - 10% adult carriers:
 • Most common cause of:
Streptocccus Pneumoniae Microbiology ... Alpha-hemolytic, Catalase Negative ... • Most common cause ... media • Important cause ... sinus • Sputum culture
Infective endocarditis - etiology and sources of infection. 
 • Native and prosthetic 
valve endocarditis
 •
Infective endocarditis ... • Native and ... prosthetic valve endocarditis ... #Sources #Causes ... #Differential #Microbiology
Differentiating NBTE from Infective Endocarditis
No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
serology: Serial negative ... Frequent false-negative ... /serology: + (Negative ... in up to 30% of cases ... #comparison #infective
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Hypercoagulable (APLAS) Microbiology ... Culture (+): ... • Coagulase-negative ... Septic Emboli Cause ... Treat underlying cause
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... Infective Endocarditis ... remain negative ... but important causes ... #Infective #Endocarditis
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
Hypercoagulable (APLAS) Microbiology ... aureus, Coagulase-negative ... Negative: • Bartonella ... Septic emboli cause ... Treat underlying cause