331 results
Causes of blood culture negative infective endocarditis

Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
Causes of blood ... culture negative ... identified with modern culture ... #culture #negative ... InfectiousDiseases #Microbiology
Capnocytophaga spp on Culture and Blood Smear
Associated w/ dog/human oral flora, can cause bacteremia in immunocompromised
Capnocytophaga spp on Culture ... oral flora, can cause ... pts From blood culture ... anaerobe; narrow Gram negative ... clinical #microscopy #microbiology
Streptocccus Pneumoniae
Microbiology: Gram Positive, Alpha-hemolytic, Catalase Negative
Epidemiology - 10% adult carriers:
 • Most common cause of:
Streptocccus Pneumoniae Microbiology ... Alpha-hemolytic, Catalase Negative ... • Most common cause ... media • Important cause ... sinus • Sputum culture
Moraxella catarrhalis on culture and microscopy
Only 1-5% of adults are colonized with this Gram neg diplococci
catarrhalis on culture ... It can be the cause ... ) - Gram negative ... #catarrhalis #culture ... microscopy #clinical #microbiology
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Hypercoagulable (APLAS) Microbiology ... Culture (+): ... • Coagulase-negative ... Septic Emboli Cause ... Treat underlying cause
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
Hypercoagulable (APLAS) Microbiology ... aureus, Coagulase-negative ... Negative: • Bartonella ... Septic emboli cause ... Treat underlying cause
My Patient with Infective Endocarditis (IE) Has Negative Blood Cultures
 - Did they receive antibiotics prior
Endocarditis (IE) Has Negative ... Blood Cultures ... antibiotics prior to cultures ... therapy - Number one cause ... of culture negative
Endocarditis Algorithm - Infective vs Noninfective Causes
Noninfective:
 • Malignancy
 • Autoimmune disease
 • Systemic infection
Native Valve
vs Noninfective Causes ... • HACEK • Culture-negative ... epidermidis • Gram-negative ... Enterococcus • Gram-negative ... #Noninfective #Causes
Microorganisms Responsible for Infective Endocarditis

Native valves:
 - Streptococcus viridans 
 - Enterococci 
 - Other streptococci
epidermidis - Gram-negative ... Histoplasma) - Culture ... negative bacilli ... streptococci - Culture ... negative #Infective
Blood culture contaminants
Grouped by gram negative vs gram positive vs other as well as never/maybe/probably
Some additional
Blood culture contaminants ... Grouped by gram negative ... #Infections #Microbiology