119 results
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
- Overview and Differential ... Hypercoagulable (APLAS) Microbiology ... Negative: • Bartonella ... Septic emboli cause ... hematuria, + RF Treatment
Blood culture contaminants
Grouped by gram negative vs gram positive vs other as well as never/maybe/probably
Some additional
Blood culture contaminants ... Grouped by gram negative ... Diseases #Infections ... #Microbiology # ... Micro #Differential
Causes of blood culture negative infective endocarditis

Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
Causes of blood ... culture negative ... #differential # ... #culture #negative ... InfectiousDiseases #Microbiology
Endocarditis Algorithm - Infective vs Noninfective Causes
Noninfective:
 • Malignancy
 • Autoimmune disease
 • Systemic infection
Native Valve
vs Noninfective Causes ... disease • Systemic infection ... • HACEK • Culture-negative ... #Noninfective #Causes ... #Differential #
Infective endocarditis - etiology and sources of infection. 
 • Native and prosthetic 
valve endocarditis
 •
and sources of infection ... • Native and ... Endocarditis #Sources #Causes ... Bacteria #Etiology #Differential ... #Microbiology #
Causes of Culture Negative Abscess - Differential Diagnosis Framework
Consider prior antibiotics as a cause of a
Causes of Culture ... - Differential ... antibiotics as a cause ... of a negative culture ... #Differential #
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... remain negative ... but important causes ... #BloodCulture #Negative ... Endocarditis #diagnosis #differential
Epidemiological Clues That May be Helpful in Defining the Etiological Diagnosis of Culture-Negative Endocarditis

#Endocarditis #Bacteria #Differential
Epidemiological Clues ... Etiological Diagnosis of Culture-Negative ... Endocarditis #Bacteria #Differential ... Microorganisms #Clues
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Neutrophil (Normal) Differential ... overlook severe infections ... likelihood of negative ... relative to both ... #Bandemia #differential
Streptocccus Pneumoniae
Microbiology: Gram Positive, Alpha-hemolytic, Catalase Negative
Epidemiology - 10% adult carriers:
 • Most common cause of:
Alpha-hemolytic, Catalase Negative ... • Most common cause ... media • Important cause ... sinus • Sputum culture ... Specificity of 97%) Treatment