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diagnosis fungal differential cardiology bcnie betadglucan biomarkers galactomannan infective management table bacteria betad bloodculture canimorsus capnocytophaga causes cnie culture dglucan
Microorganisms Responsible for Infective Endocarditis Native valves: - Streptococcus viridans - Enterococci - Other streptococci
for Infective Endocarditis ... Fungi (Candida, Aspergillus ... ) - Culture negative ... #Infective #Endocarditis ... #Differential #InfectiousDiseases
Fungal Pneumonias - Diagnosis Comparison Table • Aspergillus • Blastomyces • Candida • Coccidioides • Cryptococcus
Pneumonias - Diagnosis Comparison ... Table • Aspergillus ... Pneumonias #Diagnosis #Comparison ... #Table #microbiology ... #infectiousdiseases
Causes of blood culture negative infective endocarditis Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
blood culture negative ... infective endocarditis ... whipplei, Fungi (Aspergillus ... InfectiousDiseases ... #Microbiology #
Fungal Biomarkers: Comparing Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi •
Biomarkers: Comparing Beta-D-Glucan ... and Aspergillus ... Galactomannan Beta-D-Glucan ... Galactomannan #diagnosis #comparison ... #microbiology
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
Fungal Biomarkers: Beta-D-Glucan ... Galactomannan Beta-D-Glucan ... Coccidioides - Negative ... Cryptococcus - Negative ... Galactomannan #diagnosis #comparison
Blood Culture-Negative Infective Endocarditis (BCNIE) Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... Infective Endocarditis ... whipplei, Fungi (Aspergillus ... #Infective #Endocarditis ... differential #workup #infectiousdiseases
Capnocytophaga Pathogen: Capnocytophaga • 9 species, C. canimorsus responsible for the majority of infections • Gram-negative rod,
infections • Gram-negative ... 13%), Pneumonia, Endocarditis ... fusiform gram-negative ... Capnocytophaga #canimorsus #microbiology ... #zoonotic #infectiousdiseases
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Endocarditis Summary ... Hypercoagulable (APLAS) Microbiology ... • Coagulase-negative ... Tropheryma Whipplei • Aspergillus ... #Endocarditis
(1,3)-β-d-glucan Abundant cell wall polysaccharide, found in most fungi, except cryptococci, zygomycetes (mucor, rhizophus) and blastomyces. Sensitivity 64%-93%;
87%-100% False Negatives ... TheIDtrivia #beta ... dglucan #glucan #betad ... diagnosis #laboratory #microbiology ... #infectiousdiseases
Important Fungal Stains Mycology Lab: • Calcofluor white - Fluorochrome that binds glucans and chitin in fungal
exceptions are Aspergillus ... • India ink - "Negative ... Fungal #Stains #microbiology ... fungi #fungus #comparison
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