19 results
Causes of blood culture negative infective endocarditis

Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
Causes of blood ... culture negative ... infective endocarditis ... #Endocarditis # ... InfectiousDiseases #Microbiology
Infective endocarditis - etiology and sources of infection. 
 • Native and prosthetic 
valve endocarditis
 •
Infective endocarditis ... • Native and ... prosthetic valve endocarditis ... #Sources #Causes ... #Differential #Microbiology
My Patient with Infective Endocarditis (IE) Has Negative Blood Cultures
 - Did they receive antibiotics prior
with Infective Endocarditis ... (IE) Has Negative ... Blood Cultures ... therapy - Number one cause ... #Infective #Endocarditis
Streptocccus Pneumoniae
Microbiology: Gram Positive, Alpha-hemolytic, Catalase Negative
Epidemiology - 10% adult carriers:
 • Most common cause of:
Streptocccus Pneumoniae Microbiology ... Alpha-hemolytic, Catalase Negative ... • Most common cause ... media • Important cause ... peritonitis, and endocarditis
Plasmodium Falciparum Blood Smear.
Key features suggesting Plasmodium falciparum:
- extreme parasitemia
- normocytic RBCs (vivax, ovale prefer big
Plasmodium Falciparum Blood ... P. falciparum causes ... human malaria cases ... peripheral #clinical #microscopy ... #microbiology #
Differentiating NBTE from Infective Endocarditis
No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
from Infective Endocarditis ... serology: Serial negative ... Frequent false-negative ... cultures/serology: + (Negative ... in up to 30% of cases
Moraxella catarrhalis on culture and microscopy
Only 1-5% of adults are colonized with this Gram neg diplococci
on culture and microscopy ... It can be the cause ... Neissseria spp. negative ... ) - Gram negative ... #clinical #microbiology
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Hypercoagulable (APLAS) Microbiology ... : Blood cultures ... • Coagulase-negative ... Septic Emboli Cause ... • Blood cultures
Septic Arthritis: Pathogenesis and clinical findings
Notes:
- Septic Arthritis is typically monoarticular & the knee is involved
involved in >50% of cases ... - decr blood flow ... a +ve culture Microbiology ... S.A. can also be caused ... SepticArthritis #pathophysiology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Cryoglobulinemia, Endocarditis ... Pauci-immune mediated (Negative