17 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Cerebrovascular Disease ... , PRES Pathophysiology ... thrombosis and/or blood-brain ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Diagnosis and Management ... pANCA anti-MPO - Negative ... Evolution: Chronic disease ... #Summary #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... Post-strep GN, Lupus ... involvement: Anti-GBM Disease ... Pauci-immune mediated (Negative ... diagnosis #algorithm #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
pANCA anti-MPO - Negative ... Usual therapeutic management ... Evolution: Chronic disease ... comparison #table #rheumatology ... #diagnosis #management
Distinguishing between Inflammatory and Degenerative joint disease
Inflammatory Joint Disease
 • Swelling stimulates joint nociceptors -> Pain
Degenerative joint disease ... after > 1 hr • Blood ... Rheumatoid arthritis, Lupus ... Comparison #Versus #MSK ... JointPain #Diagnosis #pathophysiology
Intraoperative Laryngospasm and Stridor - Guidelines for Crises in Anaesthesia

❶ Call for help and inform theatre
and Stridor - Guidelines ... suction catheters, blood ... oxygen and face mask ... has developed negative-pressure ... Checklist #Diagnosis #Management
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
), RA, crystal disease ... spondyloarthropathies, lupus ... tumor • Non-bloody ... #Joint #Pain #MSK ... #rheumatology #
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
of peripheral blood ... • Autoimmune diseases ... cultures, including blood ... likelihood of negative ... #pathophysiology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Graft Versus Host Disease ... (rare), false negatives ... Borrellia (Lyme disease ... Transfusions #diagnosis #management ... #hematology #reactions
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Graft Versus Host Disease ... (rare), false negatives ... Borrellia (Lyme disease ... Transfusion #diagnosis #management ... #hematology #reactions