41 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... involvement: Anti-GBM Disease ... Pauci-immune mediated (Negative ... diagnosis #algorithm #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... pANCA anti-MPO - Negative ... Usual therapeutic management ... Evolution: Chronic disease ... #Summary #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Cerebrovascular Disease ... , PRES Pathophysiology ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis #management
Gastrointestinal Evaluation of Iron Deficiency Anemia
In patients with anemia, diagnose iron deficiency if:
 • Ferritin <
Test for celiac disease ... with serology first ... biopsy only if serology ... endoscopy only if: • Negative ... change medical management
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
intervertebral disc disease ... Stabbing) - Negative ... MeralgiaParesthetica #MSK ... #pathophysiology
Tularemia - Diagnosis and Management Summary
Francisella tularensis - Aerobic fastidious gram-negative Coccobacillus - Zoonotic Infection
 •
Diagnosis and Management ... fastidious gram-negative ... conditions Diagnosis: Serology ... Treatment: • Severe Disease ... Streptomycin • Moderate Disease
Helicobacter Pylori (H. pylori) Infection - Diagnosis and Management - GrepMed Handbook
Presentation: Dyspepsia / Peptic Ulcer
Diagnosis and Management ... / Peptic Ulcer Disease ... 50% of adults +serology ... microaerophilic, gram negative ... past infection Management
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... • Some false negative ... IgG4 #Related #Disease ... #diagnosis #management ... workup #treatment #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
- Autoimmune Rheumatologic ... Disease OLIGOARTHRITIS ... aureus • Gram-negative ... Differential #Diagnosis #MSK ... #rheumatology #
Hematuria in Post-Renal Transplant Patient
Prevalence up to 12% in the postrenal transplant patient
 • Bacterial: Escherichia
cell carcinoma (native ... , Busulfan • Disease ... #blood #urine #management ... #treatment #nephrology