10 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... Positive in 60-80% of cases ... pANCA anti-MPO - Negative ... life-threatening • Treatment ... Management #Summary #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... Erythematosus #SLE ... CNS #neurology #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... pANCA anti-MPO - Negative ... life-threatening • Treatment ... comparison #table #rheumatology ... #diagnosis #management
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... Amy Chung, MD, MSc ... Lymphoproliferative #Disorders #Classification ... #pathophysiology ... #Hematology #Diagnosis
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Autoimmune diseases: SLE ... Treatment: • ... #management #treatment ... #summary #rheumatology
In order to better classify heart failure, the American College of Cardiology Foundation and the American
Below one can see ... With treatment, ... patients with a diagnosis ... #Diagnosis #Cardiology ... #Stages #Classes
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Arthritis Differential Diagnosis ... weeks) Can Be Caused ... aureus • Gram-negative ... arthritis • SLE ... #MSK #rheumatology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Evaluate for NMO, SLE ... tested and if negative ... Disorders: - SLE ... Transverse Myelitis Treatment
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
and Differential Diagnosis ... • Autoimmune (SLE ... aureus, Coagulase-negative ... staphylococci Culture Negative ... hematuria, + RF Treatment
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Hypocomplementemia • Can cause ... phenomenon (16%) MSK ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology