22 results
Carbapenems - Antibiotics Class Overview

Imipenem/Cilastin, Meropenem, Ertapenem, Doripenem 

Spectrum: Broadest spectrum antibiotics, cover Gram positive, Gram
Class Overview ... positive, Gram negative ... resistant gram negatives ... #Pharmacology ... #Overview #Carbapenems
Daptomycin  - Antibiotics Class Overview

Mechanism: Lipopeptide antibiotic – forms transmembrane channels and depolarizes cells.
Class Overview ... No gram negative ... skin/soft tissue infections ... cidal nature) #Pharmacology ... #Overview #Daptomycin
Aminoglycosides  - Antibiotics Class Overview

Gentamicin, Tobramycin, Amikacin, Streptomycin -30S inhibitor (all IV)
Spectrum: Extremely efficacious vs.
Aminoglycosides - Antibiotics ... Class Overview ... . aerobic Gram negatives ... #Pharmacology #Antibiotics ... #Review #Overview
Tigecycline (IV) - Antibiotics Class Overview

Mechanism: Glycylcycline class - structurally related to Tetracyclines (bacteriostatic).  Only
Tigecycline (IV) - Antibiotics ... Class Overview ... and VRE), Gram negatives ... #Pharmacology #Antibiotics ... #Review #Overview
Vancomycin and Dalbavancin (lipoglycopeptide antibiotics) - Antibiotics Class Overview

Mechanism: Glycopeptide -  inhibits cell wall synthesis
) - Antibiotics ... Class Overview ... No gram negative ... #Pharmacology #Antibiotics ... #Review #Overview
IDSA Suggested Empiric Antibiotic Regimens Based on Clinical Severity for Diabetic Foot Infections
Mild (usually treated with
Suggested Empiric Antibiotic ... Regimens Based on Clinical ... Severity for Diabetic ... Foot Infections ... #pharmacology #
Antifungal Echinocandins  - Antibiotics Class Overview

Mechanism: Inhibit glucan synthesis in fungal cell wall by blocking
Echinocandins - Antibiotics ... Class Overview ... severe Candida infections ... usually works clinically ... Anidulafungin #Pharmacology
Monobactam - Aztreonam - Antibiotics Class Overview

Spectrum: only has activity vs. aerobic gram negatives, no gram
Class Overview ... . aerobic gram negatives ... due to gram-negative ... #Pharmacology #Antibiotics ... #Review #Overview
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Bandemia Overview ... Normal: < 1% Clinically ... likelihood of negative ... clinical outcomes ... #Bandemia #differential
Tetracyclines – Doxycycline, Tetracycline, Minocycline - Antibiotics Class Overview

- 30S Inhibitors (PO and IV)
Spectrum: Fairly broad
Minocycline - Antibiotics ... Class Overview ... coverage, some gram negative ... #Pharmacology #Antibiotics ... #Review #Overview