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review diagnosis endocarditis management algorithm amikacin aminoglycosides antipseudomonal antipseudomonas aztreonam bactrim carbapenems causes chf clinical colistin criticalcare dalbavancin dalvance daptomycin
Carbapenems - Antibiotics Class Overview Imipenem/Cilastin, Meropenem, Ertapenem, Doripenem Spectrum: Broadest spectrum antibiotics, cover Gram positive, Gram
Class Overview ... positive, Gram negative ... resistant gram negatives ... #Pharmacology ... #Overview #Carbapenems
Daptomycin - Antibiotics Class Overview Mechanism: Lipopeptide antibiotic – forms transmembrane channels and depolarizes cells.
Class Overview ... No gram negative ... skin/soft tissue infections ... cidal nature) #Pharmacology ... #Overview #Daptomycin
Aminoglycosides - Antibiotics Class Overview Gentamicin, Tobramycin, Amikacin, Streptomycin -30S inhibitor (all IV) Spectrum: Extremely efficacious vs.
Aminoglycosides - Antibiotics ... Class Overview ... . aerobic Gram negatives ... #Pharmacology #Antibiotics ... #Review #Overview
Tigecycline (IV) - Antibiotics Class Overview Mechanism: Glycylcycline class - structurally related to Tetracyclines (bacteriostatic). Only
Tigecycline (IV) - Antibiotics ... Class Overview ... and VRE), Gram negatives ... #Pharmacology #Antibiotics ... #Review #Overview
Vancomycin and Dalbavancin (lipoglycopeptide antibiotics) - Antibiotics Class Overview Mechanism: Glycopeptide - inhibits cell wall synthesis
) - Antibiotics ... Class Overview ... No gram negative ... #Pharmacology #Antibiotics ... #Review #Overview
Monobactam - Aztreonam - Antibiotics Class Overview Spectrum: only has activity vs. aerobic gram negatives, no gram
Class Overview ... . aerobic gram negatives ... due to gram-negative ... #Pharmacology #Antibiotics ... #Review #Overview
Tetracyclines – Doxycycline, Tetracycline, Minocycline - Antibiotics Class Overview - 30S Inhibitors (PO and IV) Spectrum: Fairly broad
Minocycline - Antibiotics ... Class Overview ... coverage, some gram negative ... #Pharmacology #Antibiotics ... #Review #Overview
Sulfonamides - Antibiotics Class Overview BACTRIM/SEPTRA (TMP/SMX) - inhibit sequential steps in Folate synthesis --> bacteriostatic Spectrum: Wide
Sulfonamides - Antibiotics ... Class Overview ... and most Gram negatives ... #Pharmacology #Antibiotics ... #Review #Overview
Causes of Myocarditis 1. Infectious Myocarditis • Bacterial - Staphylococcus, Streptococcus, Pneumococcus, Meningococcus, Gonococcus, Salmonella, Corynebacterium
Autoantigens - Infection-negative ... lymphocytic, infection-negative ... insulin-dependent diabetes ... Myocarditis #Causes #differential ... #diagnosis #cardiology
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Infectious: • Pre-existing ... • Coagulase-negative ... Marantic (NTBE) Differential ... • IV Antibiotics ... diagnosis #management #cardiology
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