31 results
Lidocaine HCl - sodium channel blocker. Local anesthetic and class 1B antiarrhythmic. Originally developed in 1943
anesthetic and class 1B antiarrhythmic ... #Pharmacology #Lidocaine ... Xylocaine #Systemic #Review
Carbapenems - Antibiotics Class Overview

Imipenem/Cilastin, Meropenem, Ertapenem, Doripenem 

Spectrum: Broadest spectrum antibiotics, cover Gram positive, Gram
positive, Gram negative ... resistant gram negatives ... infections #Pharmacology ... #Antibiotics #Review
REBEL Review 46: Corticosteroid Conversion Chart 

Glucocorticoid, Approximate Equivalent Dose (mg), Relative Anti-Inflammatory (Glucocorticoid) Potency, Relative
REBEL Review 46: ... Equivalent Dose (mg), Relative ... Glucocorticoid) Potency, Relative ... comparison #table #pharmacology
Aminoglycosides  - Antibiotics Class Overview

Gentamicin, Tobramycin, Amikacin, Streptomycin -30S inhibitor (all IV)
Spectrum: Extremely efficacious vs.
. aerobic Gram negatives ... : serious gram negative ... #Pharmacology #Antibiotics ... #Review #Overview
Running out of Analgesia and Sedation Medications due to #COVID19?  Anand Swaminathan, MD has put
options in REBEL Review ... medications #sedation #sedative ... #analgesia #pharmacology
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Antiarrhythmics ... contraction force (negative ... accpcardprn #Antiarrhythmics ... Vaughan #Williams #Pharmacology ... Classification #Classes #pathophysiology
Daptomycin  - Antibiotics Class Overview

Mechanism: Lipopeptide antibiotic – forms transmembrane channels and depolarizes cells.
No gram negative ... cidal nature) #Pharmacology ... #Antibiotics #Review
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics ... Pharmacology Summary ... to maintain a negative ... #Pharmacology # ... Classification #Classes #pathophysiology
Tigecycline (IV) - Antibiotics Class Overview

Mechanism: Glycylcycline class - structurally related to Tetracyclines (bacteriostatic).  Only
and VRE), Gram negatives ... #Pharmacology #Antibiotics ... #Review #Overview
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS)
Absolute Insulin deficit:
 - Type I DM:
Pathophysiology ... Hyperglycemic Hyperosmolar Syndrome ... insulin demand Relative ... #dka #hhs #pathophysiology