10 results
Daptomycin  - Antibiotics Class Overview

Mechanism: Lipopeptide antibiotic – forms transmembrane channels and depolarizes cells.
Daptomycin - Antibiotics ... Rapidly cidal drug ... No gram negative ... cidal nature) #Pharmacology ... #Antibiotics #Review
Vancomycin and Dalbavancin (lipoglycopeptide antibiotics) - Antibiotics Class Overview

Mechanism: Glycopeptide -  inhibits cell wall synthesis
) - Antibiotics ... No gram negative ... Drug of choice for ... #Pharmacology #Antibiotics ... #Review #Overview
Drug-Induced Prolonged QTc

QTc >500ms is an independent risk factor for developing Torsades des Pointes (TdP)
Drugs causing
Drug-Induced Prolonged ... prolongation: • Antiarrhythmics ... Risperidone • Antibiotics ... Toxicity #Toxicology #Pharmacology ... #Diagnosis #prolongation
Intern Pocket Cards - Antibiogram and Susceptibilities
VRE - MRSA - GRAM POSITIVES - GRAM NEGATIVES -
POSITIVES - GRAM NEGATIVES ... Stewardship: → What syndrome ... → What drug? ... Susceptibilities #antibiotics ... #management #pharmacology
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
Group A Strep - Drugs ... - I.e., antibiotics ... nephrotic/nephritic syndrome ... HenochScholeinPurpura #Pathophysiology ... #Diagnosis #Signs
Tetracyclines – Doxycycline, Tetracycline, Minocycline - Antibiotics Class Overview

- 30S Inhibitors (PO and IV)
Spectrum: Fairly broad
Minocycline - Antibiotics ... coverage, some gram negative ... Drug of choice for ... #Pharmacology #Antibiotics ... #Review #Overview
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
Propofol infusion syndrome ... A dissociative drug ... No pharmacologic ... (Haldol) - No pharmacologic ... #CriticalCare #diagnosis
Sulfonamides - Antibiotics Class Overview

BACTRIM/SEPTRA (TMP/SMX) - inhibit sequential steps in Folate synthesis --> bacteriostatic

Spectrum: Wide
Sulfonamides - Antibiotics ... and most Gram negatives ... including PCP PNA (drug ... #Pharmacology #Antibiotics ... #Review #Overview
Chloramphenicol - Antibiotics Class Overview

– 50S ribosomal inhibitor.   IV or PO (but PO form
E.faecium/VRE); Gram negatives ... several weeks after drug ... Gray baby syndrome ... #Pharmacology #Antibiotics ... #Review #Overview
Serotonin Syndrome: Pathogenesis and Clinical Findings
Serotonin Syndrome: Variable combination of mental status changes, autonomic instability, and
antidepressants, antibiotics ... weight loss agents, drugs ... make a clinical diagnosis ... #Pathophysiology ... #Psychiatry #Diagnosis