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rheumatology dermatology lupus sle systemic arthritis skin summary syndrome table treatment activation ana antinuclear antinxp2 antinxp2dm autoantibodies bacilliformis bartonella blastomycosis
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
40, F:M 9:1 • Clinical ... • Immunologic Workup ... pANCA anti-MPO - Negative ... Evolution: Chronic disease ... #Diagnosis #Management
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Systemic Lupus Erythematosus ... (SLE) Clinical ... Cerebrovascular Disease ... permeability Diagnosis ... #management #treatment
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Systemic Lupus Erythematosus ... pANCA anti-MPO - Negative ... Evolution: Chronic disease ... #diagnosis #management
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... Clinical history ... • Some false negative ... #diagnosis #management ... #phenotypes #workup
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Systemic lupus erythematosus ... fever syndromes Clinical ... Fever is the main clinical ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Septic Arthritis - Diagnosis and Management Summary Clinical Exam: hot, swollen, pain with passive AND active ROM
and Management ... Summary Clinical ... necrosis, Lyme disease ... viral arthritis Workup ... staphylococcus, gram negative
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Association with disease ... -15% If SLE is clinically ... Negative association ... Systemic #lupus #erythematosus ... #diagnosis #rheumatology
Ulcerative Blastomycosis Skin Lesion 57 asymptomatic M from Indiana nonpruritic, painless, progressive skin lesion lower back x
an old house & works ... Diagnosis? ... University Infectious Diseases ... Blastomycosis #SkinRash #dermatology ... #clinical #photo
Oroya Fever Hematologic disease caused by Bartonella bacilliformis Restricted to the Andes highlands of Peru & Ecuador B. bacilliformis:
Oroya Fever Hematologic ... disease caused ... bacilliformis: - Gram negative ... Lutzomyia verrucarum Clinical ... #management #Bartonella
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Systemic lupus erythematosus ... ANAs; thus, a negative ... ANA and RF (if clinical ... #diagnosis #testing
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