17 results
Daptomycin  - Antibiotics Class Overview

Mechanism: Lipopeptide antibiotic – forms transmembrane channels and depolarizes cells.
Antibiotics Class Overview ... Rapidly cidal drug ... No gram negative ... activity. ... cidal nature) #Pharmacology
Vancomycin and Dalbavancin (lipoglycopeptide antibiotics) - Antibiotics Class Overview

Mechanism: Glycopeptide -  inhibits cell wall synthesis
Antibiotics Class Overview ... positive agent with activity ... No gram negative ... Drug of choice for ... #Pharmacology #Antibiotics
Antifungal Echinocandins  - Antibiotics Class Overview

Mechanism: Inhibit glucan synthesis in fungal cell wall by blocking
Antibiotics Class Overview ... vs Candida -> Drug ... usually works clinically ... Echinocandins lack activity ... Anidulafungin #Pharmacology
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Tuberculosis Overview ... Recent infection • Pulmonary ... inhibitors • Injection drug ... • HIV: 2/3 pulmonary ... characteristic features Clinical
For my UME micro course, I made a figure that captures this terminology and lets learners
the spectrum of clinically ... contrast important drug ... common beta lactam drugs ... #antibiogram #pharmacology ... management #spectrum #table
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Tuberculosis Overview ... Recent infection • Pulmonary ... inhibitors • Injection drug ... • HIV: 2/3 pulmonary ... characteristic features Clinical
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Association with disease activity ... SLE (60-70%) & drug-induced ... -15% If SLE is clinically ... Negative association ... #rheumatology #table
Tetracyclines – Doxycycline, Tetracycline, Minocycline - Antibiotics Class Overview

- 30S Inhibitors (PO and IV)
Spectrum: Fairly broad
Antibiotics Class Overview ... coverage, some gram negative ... Has activity for ... Drug of choice for ... #Pharmacology #Antibiotics
Clinically Significant Cardiovascular Drug-Drug Interactions With OTC Supplements and Herbal Products
Angiotensin-Converting Enzyme Inhibitors (ACEIs)
 • Night-blooming
Clinically Significant ... Cardiovascular Drug-Drug ... wort - Increases activity ... supplementals #herbal #pharmacology ... #DDI #table #cardiology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
with presence of pulmonary ... have achieved negative ... #differential #algorithm ... cardiology #treatment #table ... #pharmacology