13 results
Daptomycin  - Antibiotics Class Overview

Mechanism: Lipopeptide antibiotic – forms transmembrane channels and depolarizes cells.
Rapidly cidal drug ... No gram negative ... skin/soft tissue infections ... MRSA bacteremia/endocarditis ... cidal nature) #Pharmacology
Anti-infective stewardship, including tips for using anti-infectives wisely, criteria for stepdown from IV to PO dosage
for using anti-infectives ... IV to PO anti-infectives ... #pharmacology #antibiotics ... #medications #table ... #treatment #drugs
Causes of Antibiotic Failure - Differential Diagnosis Framework
Diagnosis:
 • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Causes of Antibiotic ... Immunocompromise Treatment ... : • Antibiotic: ... lines, osteo, endocarditis ... • Secondary to Treatment
Antibiotic classification refers to the categorization of antibiotics based on their chemical structure, mechanism of action,
drugs that are used ... treat bacterial infections ... Imagine treatments ... #Antibiotics #pharmacology ... classification #table
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Causes of Fatigue ... • Malignancy Infectious ... • Endocarditis ... Chronic Obstructive Pulmonary ... Myasthenia Gravis Pharmacologic
Invasive Aspergillus (IA) - Diagnosis and Management
Aspergillus is ubiquitous in nature. Most invasive infections are caused
are caused by members ... presentations: • Pulmonary ... Endophthalmitis, Endocarditis ... this morphology Treatment ... : • Drug of choice
Differentiating NBTE from Infective Endocarditis
No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
Frequent false-negative ... of intravenous drug ... in up to 30% of cases ... large infarct - Infectious ... Marantic #diagnosis #table
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Infectious: • Pre-existing ... • Coagulase-negative ... Cerebral > Splenic, pulmonary ... Septic Emboli Cause ... • IV Antibiotics
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
polymicrobial infection ... • Most common cause ... once stable - ... Lung #Abscess #pulmonary ... #differential #causes
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
aureus, Coagulase-negative ... staphylococci Culture Negative ... Cerebral > Splenic, Pulmonary ... hematuria, + RF Treatment ... • IV antibiotics