13 results
Jaundice Evaluation Algorithm #Diagnosis #Management #EM #IM #GI #Jaundice #Hyperbilirubinemia #Workup #Evaluation #Differential #Algorithm #Direct #Indirect
Algorithm #Diagnosis ... #Management #EM ... #Hyperbilirubinemia ... #Differential # ... Algorithm #Direct
Approach to Neonatal Jaundice

Causes of pathologic hyperbilirubinemia can be classified as due to (1) increased bilirubin
Jaundice Causes ... of pathologic hyperbilirubinemia ... #Diagnosis #Peds ... #Differential # ... Workup #bilirubinemia
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
Jaundice - Differential ... Diagnosis Algorithm ... #Differential # ... Diagnosis #Algorithm ... #Causes #Hepatology
Classification of Jaundice
Unconjugated hyperbilirubinemia (predominantly indirect bilirubin)
 • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Classification of Jaundice ... (predominantly direct ... Classification #diagnosis ... #unconjugated #differential ... #causes
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm

1. Definition: T.bili elevation + >20% conjugated
2. Obtain RUQ
- Differential ... Diagnosis Algorithm ... non-ICU vs ICU causes ... #direct #bilirubin ... gastroenterology #hepatology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
breastfeeding jaundice ... and breastmilk jaundice ... and stress may cause ... Congenital #bilirubin #hepatology ... #diagnosis #gastroenterology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
activity is the diagnostic ... available for rapid diagnosis ... platelet number Direct ... WBC count and differential ... #Workup #Hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pathophysiology: • Defect ... = nonspecific (nausea ... (DIC, ascites, jaundice ... infiltration) Differential ... Liver #Pregnancy #hepatology
Ascites - Diagnostic Approach and Differential Diagnosis
The most common causes: cirrhosis, malignancy and heart failure. Approx
most common causes ... more than one cause ... shifting dullness detect ... Jcortesizaguirr #Ascites #workup ... Diagnosis #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
intralobular bile ducts causes ... hyperpigmentation • Jaundice ... bile ducts Differential ... Diagnosis: • ... #workup #hepatology