14 results
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
NSAIDS and their effects ... on the Kidney - Pathophysiology ... distal component of Nephron ... Idiosyncratic immune reaction ... #pathophysiology
Major Physiological Effects of Angiotensin II

Altered Peripheral Resistance
I. Direct vasoconstriction
II. Enhancement of peripheral noradrenergic
neurotransmission:
  A.
Physiological Effects ... Direct effect to ... excretion in distal nephron ... AngiotensinII #Pathophysiology ... #Action
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Vaughan Williams Classification ... channel blocking effects ... , Intermediate Action ... #Pharmacology #Classification ... #Classes #pathophysiology
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride
 • Cl- responsive metabolic alkalosis
Differential Diagnosis Algorithm ... blood pressure: Active ... mineralocorticoid-like effect ... Differential #Diagnosis #Algorithm ... #causes #urinary
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Mechanism and Side-effect ... constipation • Allergic reaction ... mediated cytotoxic reaction ... -> Nausea, vomiting ... #SideEffects #Pathophysiology
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Segments of the Nephron ... organic acids and bases ... Henle's loop (TAL) - Active ... tubule (DCT) - Active ... Segments #Function #Pathophysiology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Vaughan Williams Classification ... channel blocking effects ... , Intermediate Action ... #Pharmacology #Classification ... #Classes #pathophysiology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Differential Diagnosis Algorithm ... Ileostomy - NGT suction ... extracellular anion ... Differential #Diagnosis #Algorithm ... #Pathophysiology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Urinary Chloride Algorithm ... blood pressure: Active ... mineralocorticoid-like effect ... the indicated causes ... Chloride #urine #Algorithm
The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin
Inhibited Pathway caused ... decrease in the active ... The neurological effects ... use of N2O can cause ... #Pathophysiology