15 results
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
NSAIDS and their effects ... on the Kidney - Pathophysiology ... modify immune function ... Idiosyncratic immune reaction ... #pathophysiology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Urinary Chloride Algorithm ... loop or thiazide diuretics ... Vomiting/nasogastric suction ... blood pressure: Active ... mineralocorticoid-like effect
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride
 • Cl- responsive metabolic alkalosis
Differential Diagnosis Algorithm ... loop or thiazide diuretics ... Vomiting/nasogastric suction ... blood pressure: Active ... mineralocorticoid-like effect
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Segments of the Nephron ... and their Functions ... acid and most diuretics ... #Segments #Function ... #Pathophysiology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Differential Diagnosis Algorithm ... Vomiting, NGT suction ... Low Cl intake, Diuretics ... (late) • High Urine ... Cl-: Diuretics,
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
Urine chloride < 20 mmol/l - Chloride responsive (Chloride
Differential Diagnosis Algorithm ... Urine chloride ... Vomiting • NG suction ... fibrosis • Remote diuretic ... use Urine chloride
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Differential Diagnosis Algorithm ... Vomiting, NGT suction ... Low Cl intake, Diuretics ... (late) • High Urine ... Cl-: Diuretics,
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
reabsorption in the nephron ... glucose in the urine ... are similar to diuretics ... Side effects include ... have good kidney function
Major Physiological Effects of Angiotensin II

Altered Peripheral Resistance
I. Direct vasoconstriction
II. Enhancement of peripheral noradrenergic
neurotransmission:
  A.
Physiological Effects ... Altered Renal Function ... excretion in distal nephron ... AngiotensinII #Pathophysiology ... #Action
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
Algorithm for patients ... Non-reabsorbable anion ... effect: Vomiting ... Cl - Loop diuretics ... , Thiazide diuretics