9 results
Mechanisms of Loop Diuretic Action and Resistance. Panel A, loop diuretics circulate bound to protein. As
Action and Resistance ... compete with chloride ... sodium–potassium–chloride ... #Pathophysiology ... #Nephro #IM #LoopDiuretic
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride
 • Cl- responsive metabolic alkalosis
Differential Diagnosis Algorithm ... loop or thiazide diuretics ... Vomiting/nasogastric suction ... blood pressure: Active ... mineralocorticoid-like effect
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
Urine chloride < 20 mmol/l - Chloride responsive (Chloride
Differential Diagnosis Algorithm ... Vomiting • NG suction ... fibrosis • Remote diuretic ... resistant: • Current diuretic ... Differential #Diagnosis #Algorithm
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Algorithm Cl- ... loop or thiazide diuretics ... Vomiting/nasogastric suction ... diuretic use, Bartter ... mineralocorticoid-like effect
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
NSAIDS and their effects ... on the Kidney - Pathophysiology ... modify immune function ... Idiosyncratic immune reaction ... #pathophysiology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Differential Diagnosis Algorithm ... Ileostomy - NGT suction ... RENAL LOSS: - Diuresis ... • Fatigue Chloride ... #Pathophysiology
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Segments of the Nephron ... and their Functions ... acid and most diuretics ... #Segments #Function ... #Pathophysiology
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
vomiting/ nasogastric suction ... Thiazide or loop diuretics ... after renal tubule diuretic ... effect has dissipated ... Thiazide or loop diuretics
Major Physiological Effects of Angiotensin II

Altered Peripheral Resistance
I. Direct vasoconstriction
II. Enhancement of peripheral noradrenergic
neurotransmission:
  A.
Physiological Effects ... Altered Renal Function ... excretion in distal nephron ... AngiotensinII #Pathophysiology ... #Action