9 results
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Segments of the Nephron ... and their Functions ... and bases, including ... diuretics - ... #Pathophysiology
Hyperuricemia: Pathogenesis and Complications

 - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
arteriole in the nephron ... dose salicylates, diuretics ... tubule in the nephron ... Release of purine bases ... Hyperuricemia #Pathophysiology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Differential Diagnosis Algorithm ... RENAL LOSS: - Diuresis ... SIGNS: • Muscle weakness ... transport, renal function ... #Pathophysiology
Causes of Peripheral Weakness - With and Without Sensory Changes - Differential Diagnosis Algorithm
With Sensory Changes:
Causes of Peripheral ... Differential Diagnosis Algorithm ... • Motor Neuron ... Neuromuscular Junction ... #Causes
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Causes of Peripheral ... Differential Diagnosis Algorithm ... Disease Motor Neuron ... Neuromuscular Junction ... #Causes
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride
 • Cl- responsive metabolic alkalosis
Differential Diagnosis Algorithm ... loop or thiazide diuretics ... Vomiting/nasogastric suction ... poisoning • Normal acid-base ... #causes #urinary
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Urinary Chloride Algorithm ... loop or thiazide diuretics ... pressure: Active diuretic ... the indicated causes ... and potassium acid
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
lost via osmotic diuresis ... out of cells may cause ... has good renal function ... fruity odor) • Weakness ... DiabeticKetoacidosis #DKA #pathophysiology
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Acid Base Disorders ... - Vomiting, NG suction ... Volume depletion (diuresis ... Neuromuscular weakness ... ABG #bloodgas #Acid