10 results
Causes of Peripheral Weakness - With and Without Sensory Changes - Differential Diagnosis Algorithm
With Sensory Changes:
Causes of Peripheral ... Differential Diagnosis Algorithm ... • Motor Neuron ... Neuromuscular Junction ... #Causes
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Differential Diagnosis Algorithm ... RENAL LOSS: - Diuresis ... SIGNS: • Muscle weakness ... Hypotension • AMS ... #Pathophysiology
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Causes of Peripheral ... Differential Diagnosis Algorithm ... Disease Motor Neuron ... Neuromuscular Junction ... #Causes
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Segments of the Nephron ... and their Functions ... organic acids and bases ... acid and most diuretics ... #Pathophysiology
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Definition: • Functional ... • Caused by splanchnic ... Pathophysiology: ... • Tubular function ... be substituted as
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... disrupt cellular function ... - Causes progressive ... weakness in the ... bulbar region, Weakness
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
lost via osmotic diuresis ... out of cells may cause ... has good renal function ... fruity odor) • Weakness ... DiabeticKetoacidosis #DKA #pathophysiology
Hypophosphatemia and Hypoxia - Pathophysiology

↓ Phosphate leads to ↓ red cell 2,3-DPG and a  reduction
and Hypoxia - Pathophysiology ... Phosphate does also ... impacts respiratory function ... is a cause of refractory ... respiratory #hypoxia #pathophysiology
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
Manifestations Causes ... gravidarum - Diuretic ... Hyperkinetic LVEF is also ... extremities - Muscle weakness ... beriberi #nutrition #pathophysiology
Evaluation of Recurrent Falls

Core Concept:
Maintaining an upright posture requires the integrated function of multiple systems.
Disruption in
the integrated function ... Myopathies - Motor neuron ... disease (ALS) ... • Clues: Focal weakness ... fear of falling, functional