10 results
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Segments of the Nephron ... and their Functions ... acid and most diuretics ... #Segments #Function ... #Pathophysiology
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
on the Kidney - Pathophysiology ... modify immune function ... distal component of Nephron ... absorption in distal nephron ... Idiosyncratic immune reaction
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride
 • Cl- responsive metabolic alkalosis
Differential Diagnosis Algorithm ... loop or thiazide diuretics ... Vomiting/nasogastric suction ... blood pressure: Active ... metabolic acidosis: Diabetic
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Ileostomy - NGT suction ... RENAL LOSS: - Diuresis ... transport, renal function ... Gastrointestinal function ... #Pathophysiology
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
class of anti-diabetic ... reabsorption in the nephron ... are similar to diuretics ... have good kidney function ... Medications #DM2 #Diabetes
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Urinary Chloride Algorithm ... loop or thiazide diuretics ... Vomiting/nasogastric suction ... blood pressure: Active ... metabolic acidosis • Diabetic
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
Diabetic Ketoacidosis ... lost via osmotic diuresis ... has good renal function ... 3) Follow the anion ... DiabeticKetoacidosis #DKA #pathophysiology
Major Physiological Effects of Angiotensin II

Altered Peripheral Resistance
I. Direct vasoconstriction
II. Enhancement of peripheral noradrenergic
neurotransmission:
  A.
Altered Renal Function ... excretion in distal nephron ... AngiotensinII #Pathophysiology ... #Action
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
disease states Pathophysiology ... pain, loss of function ... A reaction to phagocytosed ... • Medications (diuretics
Evaluation of Recurrent Falls

Core Concept:
Maintaining an upright posture requires the integrated function of multiple systems.
Disruption in
the integrated function ... neuropathy (e.g., diabetic ... Myopathies - Motor neuron ... limited range of motion ... fear of falling, functional