11 results
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... of Action Diuretics ... Thiazides 5) Aldosterone ... #Pathophysiology ... #Action #nephrology
Flowchart of the function of the renin-angiotensin aldosterone system (RAAS)

#renin #angiotensin #aldosterone #system #RAAS #system #algorithm
Flowchart of the function ... renin-angiotensin aldosterone ... #angiotensin #aldosterone ... #RAAS #system #algorithm ... #pathophysiology
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Segments of the Nephron ... and their Functions ... acid and most diuretics ... #Segments #Function ... #Pathophysiology
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
on the Kidney - Pathophysiology ... modify immune function ... distal component of Nephron ... absorption in distal nephron ... Idiosyncratic immune reaction
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
Differential Diagnosis Algorithm ... Vomiting • NG suction ... tubular transport • Diuretics ... • Aldosterone-secreting ... Differential #Diagnosis #Algorithm
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Ileostomy - NGT suction ... RENAL LOSS: - Diuresis ... transport, renal function ... Gastrointestinal function ... #Pathophysiology
Major Physiological Effects of Angiotensin II

Altered Peripheral Resistance
I. Direct vasoconstriction
II. Enhancement of peripheral noradrenergic
neurotransmission:
  A.
Altered Renal Function ... Release of aldosterone ... excretion in distal nephron ... AngiotensinII #Pathophysiology ... #Action
Causes of Hypokalemia - Differential Diagnosis Algorithm
Decreased intake (rare cause in isolation)
GI loss - Urine loss
Differential Diagnosis Algorithm ... Vomiting • NG suction ... contracted • Loop diuretics ... syndrome • Thiazide diuretics ... Differential #Diagnosis #Algorithm
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Differential Diagnosis Algorithm ... Vomiting, NGT suction ... Low Cl intake, Diuretics ... High Urine Cl-: Diuretics ... aldosteronism *Due to aldosterone
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
lost via osmotic diuresis ... has good renal function ... 3) Follow the anion ... DiabeticKetoacidosis #DKA #pathophysiology