12 results
Mechanisms of Loop Diuretic Action and Resistance. Panel A, loop diuretics circulate bound to protein. As
Mechanisms of Loop Diuretic ... Panel A, loop diuretics ... (NKCC2), which is ... #Pathophysiology ... #Nephro #IM #LoopDiuretic
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Segments of the Nephron ... and their Functions ... acid and most diuretics ... #Segments #Function ... #Pathophysiology
Hyperuricemia: Pathogenesis and Complications

 - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
arteriole in the nephron ... dose salicylates, diuretics ... tubule in the nephron ... Incr Breakdown of DNA ... Hyperuricemia #Pathophysiology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
Ketoacidosis (DKA ... , body K+ is lost ... via osmotic diuresis ... has good renal function ... #pathophysiology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Differential Diagnosis Algorithm ... RENAL LOSS: - Diuresis ... transport, renal function ... Gastrointestinal function ... #Pathophysiology
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
reabsorption in the nephron ... are similar to diuretics ... have good kidney function ... Each is available
Irritable Bowel Syndrome (IBS) - Pathophysiology, Diagnosis and Management Algorithm
Risk factors: Previous acute enteric infection, Female
Bowel Syndrome (IBS ... ) - Pathophysiology ... and Management Algorithm ... Younger age, Other functional ... Pregabalin #IBS
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Hypokalemia Evaluation Algorithm ... evaluating hypokalemia is ... Alkalosis: Emesis, Diuretics ... RTA, Distal RTA, DKA ... Hypokalemia #diagnosis #Algorithm
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Urinary Chloride Algorithm ... loop or thiazide diuretics ... Vomiting/nasogastric suction ... pressure: Active diuretic ... Chloride #urine #Algorithm
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
It is important ... hemodynamics and cardiac function ... excreted using diuretics ... “Warm & Dry” is ... #differential #algorithm