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diagnosis management rheumatology treatment hemophagocytic hlh lymphohistiocytosis pathophysiology rosc table acid acls algorithm ebm epinephrine hemeonc hepatology nephrology renal survival
Evidence for Epinephrine in OHCA. ROSC != Neuro Intact Survival #EBM #Prehospital #Epinephrine #ROSC #OHCA
Epinephrine in OHCA ... Epinephrine #ROSC #OHCA ... #ACLS #NeuroIntact
Table 1 – Studies evaluating epinephrine - The Bottom Line: Epinephrine can increase ROSC, but it
Epinephrine #ROSC #OHCA ... #ACLS #NeuroIntact
In July 2015 the ACC/AHA proposed and published an algorithm to help stratify cardiac arrest patients
emergent cath lab activation ... CardiacArrest #Algorithm #OHCA ... CathLab #NSTEMI #Activation
Tranexamic Acid - Indications and Pharmacology Pharmacokinetics: • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Inhibits plasminogen activation ... reduces complement activation ... #Pharmacology #hematology
Tranexamic Acid: Mechanism of Action - TXA is an anti-fibrinolytic - TXA is a synthetic analog
fibrin → preventing activation ... pathophysiology #hematology
Pathophysiology of Hypocomplementemic Urticarial Vasculitis C1q/anti-C1q antibiody -> Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Complement Pathway Activation ... Pathophysiology #Rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... MAS #Macrophage #Activation ... Diagnosis #Management #Hematology ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... IFN-y) → Excessive activation ... treatment #summary #rheumatology
Sickle Cell Disease - Pathophysiology of disease and complications Due to the deformed shape, HbS induces
membrane proteins and activating ... Complications #Hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
sequestration and activation ... Transfusion #Reactions #hematology
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