20 results
Evidence for Epinephrine in OHCA.  ROSC != Neuro Intact Survival 
#EBM #Prehospital #Epinephrine #ROSC #OHCA
Epinephrine in OHCA ... Epinephrine #ROSC #OHCA ... #ACLS #NeuroIntact
Table 1 – Studies evaluating epinephrine - The Bottom Line: Epinephrine can increase ROSC, but it
Epinephrine #ROSC #OHCA ... #ACLS #NeuroIntact
In July 2015 the ACC/AHA proposed and published an algorithm to help stratify cardiac arrest patients
emergent cath lab activation ... CardiacArrest #Algorithm #OHCA ... CathLab #NSTEMI #Activation
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
with host -> Activation ... pathophysiology #diagnosis #signs
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
synthesis of IGF1R -> Activation ... activates lipolysis Signs
Chagas Disease - Acute, Chronic and Reactivation 

Acute Chagas
 - 95% asymptomatic
 - Chagoma (Romana's sign),
Acute, Chronic and Reactivation ... Chagoma (Romana's sign ... Indeterminate - No signs ... Southern Cone Reactivation ... Acute #Chronic #Reactivation
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
causing lesions and activating ... Pathophysiology #Diagnosis #Signs
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
tissue site - Activation ... Pathophysiology #Diagnosis #Signs
Photophobia and Headache - Differential Diagnosis Framework

Why?
• The coexistence of photophobia and headache suggests the potential
result from photic activation ... meningeal irritation signs
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
excessive macrophage activation ... Diagnosis: HLH signs