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diagnosis management differential leukemia mds myelodysplastic pharmacology anemia aplastic chemotherapy chronic classification cll cyp3a4 diuresis diuretics doac emergencies excretion hodgkins
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
Diagnosis Framework HEMATOLOGIC ... Hyperviscosity Syndrome ... • Early death Neutropenic ... coma SIADH: • Hyponatremia ... differential #diagnosis #cancer
Approach to the Rash in a an oncology patient - MINT-C Mnemonic M - Malignancy: Leukemia cutis,
the Rash in a an oncology ... Dermatoses: Sweet Syndrome ... Gangrenosum, NEH T - Treatment ... differential #diagnosis #cancer ... MINTC #Mnemonic #dermatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... only curative treatment ... Myelodysplastic #Syndrome ... #hematology #oncology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Causes: - Idiopathic ... , breast CA - Hematologic ... Treatment: - Systemic ... #diagnosis #dermatology ... #oncology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓) of cytochrome p450 CYP3A4 and P-glycoprotein. DOACs are substrates
interactions) Cancer-treatment ... #Chemotherapy #Oncology ... #Hematology #Interactions ... #Table #Pharmacology
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
• Hyponatremia ... Kidney stones caused ... Tolvaptan) • Treatment ... and euvolemic hyponatremia ... #Medications #Table
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... microglobulin Treatment ... • Richter’s Syndrome ... diagnosis #workup #oncology ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... and petechiae Causes ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Out Secondary Causes ... factor (GCSF) treatments ... marrow studies Treatment ... #diagnosis #hematology ... #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... Lymphoma (90-95% of cases ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
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