17 results
Hypernatremia Differential Diagnosis Algorithm - Diabetes Insipidus Workup

Step #1 - Consider the history
Step #2 - Assess
Diagnosis Algorithm ... Workup Step #1 ... history Step #2 ... Management #Algorithm #Sodium ... #nephrology #insipidus
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Causes of Hypernatremia ... - Differential Diagnosis ... • Nephrogenic ... #Causes #nephrology ... #sodium #high
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis ... Workup Algorithm 1) ... renal mechanism 2) ... Euvolemic: Diabetes insipidus ... #sodium
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Diagnosis Algorithm ... water retention 1) ... Serum Osmolarity 2) ... Low Uric Acid → SIADH ... #Algorithm #nephrology
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Hypernatremia Diagnosis ... Workup Step 1 ... Repeat the sodium ... Step 2. ... EUVOLEMIC • SIADH
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Pathophysiology 1) ... Neurological event 2) ... Sodium loss from ... Pathophysiology #diagnosis ... #nephrology #hyponatremia
Hypernatremia - Differential Diagnosis and Treatment
Hypernatremia is almost always due to unreplaced water loss (free water
water unavailable 2) ... post-obstructive 3) Diabetes Insipidus ... : neurogenic, nephrogenic ... ([Na] / 140) - 1) ... #sodium
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
cell epithelial sodium ... of epithelial sodium ... diabetes insipidus ... Defects #Kidney #Nephrology ... #Diagnosis #Differential
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
+K / serum Na >1 ... , Renal Sodium loss ... #differential #diagnosis ... #table #sodium ... #nephrology
SIADH Treatment Options
1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
Options 1. ... Basically anything 2. ... purposes, restrict to 1 ... promoting passive sodium ... #Management #hyponatremia