16 results
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Causes of Hypernatremia ... • Osmotic diuresis ... insipidus • Nephrogenic ... Diagnosis #Causes #nephrology ... #sodium #high
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
• Euvolemic (Low ... • Hypovolemic: Diuretics ... osmotic (solute) diuresis ... Workup #Algorithm #nephrology ... #sodium
True Hyponatremia Differential Algorithm

Instead (or in addition) of volume status examination, check urine sodium and serum
low, uric acid ... high in hypovolemic ... high and uric acid ... low in euvolemic ... Algorithm #Diagnosis #Nephrology
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential ... Uric Acid - Low ... Acid → SIADH - High ... Diagnosis #Algorithm #nephrology ... #sodium #low #uricacid
Causes of Hypernatremia - Differential Diagnosis Algorithm
Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L
High
water loss, Serum Sodium ... >145 mmol/L High ... administration • Osmotic diuresis ... mannitol, glucosuria Low ... #Nephrology #Differential
Hypernatremia - Differential Diagnosis and Treatment
Hypernatremia is almost always due to unreplaced water loss (free water
urine osm (in DI; high ... unavailable 2) Osmotic Diuresis ... Diabetes Insipidus: neurogenic ... #management #nephrology ... #sodium
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
: SIADH, Renal Sodium ... can be high or ... low Uosm), Hypothyroidism ... Primary polydipsia), Low ... #nephrology
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
Modified Hyponatremia ... , Medications (diuretics ... Primary polydipsia, Low ... Algorithm #diagnosis #sodium ... #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
; High-Ceiling Diuretics ... nephrotic syndrome • Hyponatremia ... Tolvaptan) • Treatment ... and euvolemic hyponatremia ... #Nephrology #Pharmacology
Lower Extremity Dermatomes and Myotomes
Reflexes: 
 • Knee - L2, L3, L4
 • Ankle - S1
and Myotomes Reflexes ... Conditions: • Cauda Equina ... Syndrome - Low ... dysaesthesia, neurogenic ... Myotomes #diagnosis #neurology