30 results
Hypernatremia Differential Diagnosis Algorithm - Diabetes Insipidus Workup

Step #1 - Consider the history
Step #2 - Assess
Hypernatremia Differential ... history Step #2 ... DrEricStrong #Hypernatremia ... #Management #Algorithm ... #Sodium #nephrology
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Causes of Hypernatremia ... insipidus • Nephrogenic ... administration #Hypernatremia ... Diagnosis #Causes #nephrology ... #sodium #high
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Hypernatremia - ... renal mechanism 2) ... insipidus (central or nephrogenic ... Workup #Algorithm #nephrology ... #sodium
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Hypernatremia Diagnosis ... Repeat the sodium ... Step 2. ... mmol/L - true hyponatremia ... Workup #Algorithm #Nephrology
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential ... Serum Osmolarity 2) ... Osmolarity 3) Urine Sodium ... Diagnosis #Algorithm #nephrology ... #sodium #low #uricacid
Hypernatremia - Differential Diagnosis and Treatment
Hypernatremia is almost always due to unreplaced water loss (free water
, Dehydration: neurologic ... water unavailable 2) ... Diabetes Insipidus: neurogenic ... Diagnosis #Treatment #management ... #nephrology #sodium
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Neurological event 2) ... Sodium loss from ... Pathophysiology #diagnosis #nephrology ... #hyponatremia #
Status Epilepticus Pharmacotherapy Guide

 • Phenytoin and Fosphenytoin
 • Valproate Sodium
 • Levetiracetam
 • Lacosamide
 •
• Valproate Sodium ... #Epilepticus #Pharmacology ... #neurology #management
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
cell epithelial sodium ... of epithelial sodium ... - Vasopressin-2 ... receptor or aquaporin-2 ... Defects #Kidney #Nephrology
Hyponatremia Correction
1. Indications for Hypertonic Saline: seizure, coma, focal findings
   - typically occurs with
Hyponatremia Correction ... increasing Na ~5mEq 2. ... Overcorrection of Hyponatremia ... Correction #goal #rate #management ... #nephrology