15 results
Hypernatremia Differential Diagnosis Algorithm - Diabetes Insipidus Workup

Step #1 - Consider the history
Step #2 - Assess
Diagnosis Algorithm ... - Diabetes Insipidus ... Workup Step ... history Step #2 ... Management #Algorithm #Sodium
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Causes of Hypernatremia ... - Differential Diagnosis ... insipidusNephrogenic ... diabetes insipidus ... Causes #nephrology #sodium
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
renal mechanism 2) ... • Euvolemic: Diabetes ... insipidus (central ... or nephrogenic) ... #nephrology #sodium
Classification of Diabetes Insipidus

Central or neurogenic diabetes insipidus:
 - Congenital - Structural malformations affecting the hypothalamus
Diabetes Insipidus ... diabetes insipidus ... diabetes insipidus ... mutations in AQP-2 ... #Diabetes #Insipidus
Etiologies of Hypernatremia - Differential Diagnosis
GI losses / Insensible losses
Sodium Overload
Transcellular Movement of Water
Central Diabetes Insipidus
Etiologies of Hypernatremia ... - Differential Diagnosis ... Insensible losses Sodium ... Insipidus (Decr ... Diabetes Insipidus
Shock Types and Classification
DISTRIBUTIVE 66%
 • Sepsis/SIRS, anaphylaxis, adrenal insufficiency, liver failure, toxins, spinal/neurogenic
 • Warm
Shock Types and ... toxins, spinal/neurogenic ... Wet OBSTRUCTIVE 2% ... #Types #Classification ... #diagnosis #differential
Hypernatremia - Diagnostic Evaluation Algorithm
Step 1: Consider history. Most patients presenting with hypernatremia are either very
Diagnostic Evaluation ... Step 2: Check Uosm ... determine the type ... #Diagnosis #Workup ... Evaluation #Algorithm #Sodium
Hypernatremia - Differential Diagnosis and Treatment
Hypernatremia is almost always due to unreplaced water loss (free water
Differential Diagnosis ... water unavailable 2) ... post-obstructive 3) Diabetes ... Insipidus: neurogenic ... management #nephrology #sodium
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
cell epithelial sodium ... of epithelial sodium ... diabetes insipidus ... - Vasopressin-2 ... Kidney #Nephrology #Diagnosis
Shock Types - Classification
State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
Shock Types - Classification ... tissue perfusion 2. ... to infection • Neurogenic ... due to loss of Sodium ... #types #diagnosis