17 results
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis ... Workup Algorithm ... renal mechanism 2) ... #Workup #Algorithm ... #nephrology #sodium
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Hypernatremia Diagnosis ... Repeat the sodium ... Step 2. ... #Diagnosis #Workup ... #Algorithm #Nephrology
Hypernatremia Differential Diagnosis Algorithm - Diabetes Insipidus Workup

Step #1 - Consider the history
Step #2 - Assess
Diagnosis Algorithm ... Diabetes Insipidus Workup ... history Step #2 ... Management #Algorithm #Sodium ... #nephrology #insipidus
Etiologies of Hypernatremia - Differential Diagnosis
GI losses / Insensible losses
Sodium Overload
Transcellular Movement of Water
Central Diabetes Insipidus
- Differential Diagnosis ... Insensible losses Sodium ... sensitivity in kidneys ... ) - Medications ... #Table #Causes
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Inherited Defects in Kidney ... cell epithelial sodium ... of epithelial sodium ... #Nephrology #Diagnosis ... #Differential #Table
Acute Kidney Injury (AKI) - Differential Diagnosis Framework

PRE-Renal AKI:
 • Hypovolemia
 • Congestion
 • Medications
 •
Acute Kidney Injury ... Congestion • Medications ... Infection-mediated, Drug-induced ... External obstruction, Neurogenic ... #nephrology
Hypernatremia - Differential Diagnosis and Treatment
Hypernatremia is almost always due to unreplaced water loss (free water
Differential Diagnosis ... water unavailable 2) ... Diabetes Insipidus: neurogenic ... Treatment #management #nephrology ... #sodium
Drug Induced Kidney Injury
 • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy
 • Osmotic
Drug Induced Kidney ... , ACEI/ARB, IL-2 ... #differential #diagnosis ... #algorithm #nephrology ... #Medications
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
disequilibrium syndrome • Diagnosis ... and euvolemic hyponatremia ... Excretion #Diuresis #Nephrology ... #Pharmacology #Medications ... #Table
Numerous drugs taken by elderly persons can affect water balance by direct action on the kidney
Numerous drugs taken ... (Table IV). ... #Diagnosis #Pharmacology ... #Geriatrics #Hyponatremia ... #Medications #DrugInduced