11 results
Etiologies of Hypernatremia - Differential Diagnosis
GI losses / Insensible losses
Sodium Overload
Transcellular Movement of Water
Central Diabetes Insipidus
Etiologies of Hypernatremia ... Insensible losses Sodium ... congenital disorders Nephrogenic ... sensitivity in kidneys ... Diagnosis #Table #Causes
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
irrigation • Management ... • Hyponatremia ... stones caused by ... and euvolemic hyponatremia ... Diuresis #Nephrology #Pharmacology
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
Hyponatremia (<135 ... the hyponatremia ... True hyponatremia ... collecting duct in the kidneys ... The activation of
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
is usually caused ... the underlying cause ... demyelination syndrome ... Diagnosis #Treatment #management ... #nephrology #sodium
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
and Inotropes - Pharmacology ... • Higher doses cause ... antidiuretic effect at kidney ... dependent receptor activation ... #Summary #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... Heart, lung, and kidney ... 10,000 ng/mL • Hyponatremia ... MAS #Macrophage #Activation ... #Management #Hematology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Dehydration - Loss of sodium ... conditions - Neurogenic ... heat illness → Hypernatremia ... involvement: Muscles, Kidneys ... differential #diagnosis #causes
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Framework and Management ... Summary Causes ... Hyperuricemia • Hyponatremia ... nephrotoxicity to kidney ... #causes #treatment
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Hepatorenal Syndrome ... • Caused by splanchnic ... sympathetic + ADH activation ... • Urine sodium ... #Hepatorenal #Syndrome
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
forward flow to the kidneys ... acute coronary syndrome ... the determined cause ... differential #algorithm #management ... icu #clinical #pharmacology