12 results
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
• Hypovolemic: Diuretics ... osmotic (solute) diuresis ... Hypervolemic: Conn syndrome ... , Cushing syndrome ... Algorithm #nephrology #sodium
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
Approach to Hypotonic Hyponatremia ... : SIADH, Renal Sodium ... loss (diuretics ... Cirrhosis, Nephrotic syndrome ... diagnosis #table #sodium
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
irrigation • Management ... • Hyponatremia ... • Nephrogenic ... and euvolemic hyponatremia ... #Nephrology #Pharmacology
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
: • ADH ON (UOsm ... Cirrhosis, Nephrotic syndrome ... , Medications (diuretics ... salt wasting • ADH ... Algorithm #diagnosis #sodium
Etiologies of Hypernatremia - Differential Diagnosis
GI losses / Insensible losses
Sodium Overload
Transcellular Movement of Water
Central Diabetes Insipidus
Etiologies of Hypernatremia ... Insensible losses Sodium ... Insipidus (Decr ADH ... Insipidus (Incr ADH ... sensitivity in kidneys
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
Hyponatremia (<135 ... True hyponatremia ... release of anti-diuretic ... collecting duct in the kidneys ... #hyponatremia #ADH
Hypernatremia - Differential Diagnosis and Treatment
Hypernatremia is almost always due to unreplaced water loss (free water
unavailable 2) Osmotic Diuresis ... Diabetes Insipidus: neurogenic ... , nephrogenic 4 ... Diagnosis #Treatment #management ... #nephrology #sodium
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
majority of cases, ADH ... 2) Is ADH elevated ... demyelination syndrome ... Diagnosis #Treatment #management ... #nephrology #sodium
Management of Hyponatremia
Hypertonic Saline - Only indicated if patient has severe symptoms + Na < 125
Give
Management of Hyponatremia ... Diuretics ... Add Diuretics, Consider ... #Management #algorithm ... #treatment #sodium
Acute Kidney Injury (AKI) - Management Principles
Prerenal - Correct hemodynamic derangements:
 • If low preload →
Acute Kidney Injury ... (AKI) - Management ... high preload → Diuretics ... • Hepatorenal syndrome ... ureteral stent(s) • Neurogenic