21 results
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Cerebral Salt Wasting ... Neurological event 2) Sodium ... Pathophysiology #diagnosis #nephrology ... #hyponatremia # ... comparison
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
Modified Hyponatremia ... Cirrhosis, Nephrotic syndrome ... Reset osmostat, Cerebral ... Algorithm #diagnosis #sodium ... #nephrology
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
insipidus (central or nephrogenic ... Hypervolemic: Conn syndrome ... , Cushing syndrome ... Workup #Algorithm #nephrology ... #sodium
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Causes of Hypernatremia ... insipidus • Nephrogenic ... administration #Hypernatremia ... Diagnosis #Causes #nephrology ... #sodium #high
Hypernatremia Classification and Features According to Volume Status
 - Hypervolemic hypernatremia - Cushing's syndrome, Primary hyperaldosteronism,
Hypernatremia Classification ... - Cushing's syndrome ... Gestational DI, Nephrogenic ... Features #Diagnosis #Comparison ... #Table #Nephrology
Volume Based Approach to Hyponatremia
Hypovolemic, Serum uric acid >4
 • Urine Na <20: Extra-renal losses
 •
Based Approach to Hyponatremia ... Renal losses, Cerebral ... Cirrhosis, Nephrotic syndrome ... algorithm #diagnosis #sodium ... #low #nephrology
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Hypernatremia Diagnosis ... Repeat the sodium ... mmol/L - true hyponatremia ... • nephrotic syndrome ... Workup #Algorithm #Nephrology
Hypernatremia - Differential Diagnosis and Treatment
Hypernatremia is almost always due to unreplaced water loss (free water
Diabetes Insipidus: neurogenic ... , nephrogenic 4 ... patients at risk for cerebral ... Treatment #management #nephrology ... #sodium
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
: SIADH, Renal Sodium ... Insufficiency, Cerebral ... Cirrhosis, Nephrotic syndrome ... diagnosis #table #sodium ... #nephrology
Causes of Seizures - Differential Diagnosis Algorithm
Unprovoked - Epilepsy:
 • Focal: Simple, Complex
 • Generalized: Absence,
Hypertension, ICH, Cerebral ... vasoconstriction syndrome ... Hyperglycemia, Hyponatremia ... Hypocalcemia, Cerebral ... Algorithm #Causes #neurology