15 results
Hypernatremia Classification and Features According to Volume Status
 - Hypervolemic hypernatremia - Cushing's syndrome, Primary hyperaldosteronism,
- Cushing's syndrome ... Gestational DI, Nephrogenic ... , Loop diuretics ... Features #Diagnosis #Comparison ... #Table #Nephrology
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Causes of Hypernatremia ... • Osmotic diuresis ... insipidus • Nephrogenic ... Diagnosis #Causes #nephrology ... #sodium #high
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
• Hypovolemic: Diuretics ... osmotic (solute) diuresis ... , Cushing syndrome ... Workup #Algorithm #nephrology ... #sodium
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Hypernatremia Diagnosis ... Repeat the sodium ... volume loss - diuretics ... • nephrotic syndrome ... Workup #Algorithm #Nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
irrigation • Management ... • Hyponatremia ... • Nephrogenic ... and euvolemic hyponatremia ... #Nephrology #Pharmacology
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
Modified Hyponatremia ... Cirrhosis, Nephrotic syndrome ... , Medications (diuretics ... Algorithm #diagnosis #sodium ... #nephrology
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Neurological event 2) Sodium ... ) Naturiesis → diuresis ... Pathophysiology #diagnosis #nephrology ... #hyponatremia # ... comparison
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
: SIADH, Renal Sodium ... loss (diuretics ... Cirrhosis, Nephrotic syndrome ... diagnosis #table #sodium ... #nephrology
Hypernatremia - Differential Diagnosis and Treatment
Hypernatremia is almost always due to unreplaced water loss (free water
unavailable 2) Osmotic Diuresis ... Diabetes Insipidus: neurogenic ... , nephrogenic 4 ... Diagnosis #Treatment #management ... #nephrology #sodium
Hyponatremia Correction
1. Indications for Hypertonic Saline: seizure, coma, focal findings
   - typically occurs with
Hyponatremia Correction ... Demyelination Syndrome ... 3cc/kg/h, loop diuretics ... Correction #goal #rate #management ... #nephrology