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diagnosis differential treatment neurology causes hyponatremia table algorithm barre cerebritis cns correction defects diuresis diuretics encephalopathy epithelial erythematosus excretion gitelman
Hypernatremia - Differential Diagnosis Workup Algorithm 1) Check Urine Osmolality: > 600 mOsm/kg - Implies extrarenal mechanism
insipidus (central or nephrogenic ... Hypervolemic: Conn syndrome ... , Cushing syndrome ... Workup #Algorithm #nephrology ... #sodium
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
cell epithelial sodium ... of epithelial sodium ... renal tubular acidosis ... -2 deficiency Nephrogenic ... Defects #Kidney #Nephrology
Hypernatremia - Differential Diagnosis and Treatment Hypernatremia is almost always due to unreplaced water loss (free water
Hypernatremia - ... Diabetes Insipidus: neurogenic ... , nephrogenic 4 ... Diagnosis #Treatment #management ... #nephrology #sodium
Hyponatremia Correction 1. Indications for Hypertonic Saline: seizure, coma, focal findings - typically occurs with
Hyponatremia Correction ... Hypertonic Saline: seizure ... Demyelination Syndrome ... Correction #goal #rate #management ... #nephrology
Hyponatremia - Diagnosis and Treatment Hyponatremia is usually caused by the inability to excrete water normally.
Hyponatremia - Diagnosis ... demyelination syndrome ... of symptomatic (seizures ... Diagnosis #Treatment #management ... #nephrology #sodium
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
Dehydration - Loss of sodium ... conditions - Neurogenic ... heat illness → Hypernatremia ... Collapse: • Pathophysiology ... consciousness, Coma/seizure
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
irrigation • Management ... • Hyponatremia ... • Nephrogenic ... and euvolemic hyponatremia ... Excretion #Diuresis #Nephrology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
thiazide-sensitive sodium ... Renal tubular acidosis ... tachycardia • Seizures ... #diagnosis #nephrology ... #management #pathophysiology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
• Headache • Seizures ... • Headache • Seizures ... Etiology: • Pathophysiology ... #diagnosis #management ... #neurology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Movement disorders, Seizure ... Disease, PRES Pathophysiology ... Erythematosus #SLE #CNS #neurology ... cerebritis #diagnosis #management
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