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diagnosis differential causes hyponatremia management algorithm treatment rhabdomyolysis anticoagulation citrate defects ebv epithelial gitelman heat heatstroke hyperkalemia hypotonic hypovolemia illness
Modified Hyponatremia Algorithm Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants Hypotonic Hyponatremia: • ADH ON (UOsm > 100):
ON (UNa < 30): Hypovolemia ... Cirrhosis, Nephrotic syndrome ... Primary polydipsia, Low ... Algorithm #diagnosis #sodium ... #nephrology
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
can be high or low ... Present (Uosm ≥100): Hypovolemia ... Cirrhosis, Nephrotic syndrome ... differential #diagnosis #table ... #sodium #nephrology
Etiologies of Hypernatremia - Differential Diagnosis GI losses / Insensible losses Sodium Overload Transcellular Movement of Water Central Diabetes Insipidus
Etiologies of Hypernatremia ... Insensible losses Sodium ... Insipidus (Decr ADH ... hypercalcemia - Chronic hypokalemia ... Differential #Diagnosis #Table
Hypernatremia - Differential Diagnosis Workup Algorithm 1) Check Urine Osmolality: > 600 mOsm/kg - Implies extrarenal mechanism
• Euvolemic (Low ... Hypervolemic: Conn syndrome ... , Cushing syndrome ... Workup #Algorithm #nephrology ... #sodium
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
cell epithelial sodium ... of epithelial sodium ... renal tubular acidosis ... Defects #Kidney #Nephrology ... #Differential #Table
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
asymptomatic to seizures ... stimulated in states of low ... activated in states of low ... #hyponatremia #ADH ... #RAAS #Hypovolemia
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
thiazide-sensitive sodium ... alkalosis • Normal or low ... Renal tubular acidosis ... tachycardia • Seizures ... #diagnosis #nephrology
Hyponatremia - Diagnosis and Treatment Hyponatremia is usually caused by the inability to excrete water normally.
majority of cases, ADH ... demyelination syndrome ... of symptomatic (seizures ... Treatment #management #nephrology ... #sodium
Hyponatremia - Differential Algorithm Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP Hypotonic Hyponatremia: • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
Hyponatremia - Differential ... : • Hypovolemia ... Cirrhosis, Nephrotic Syndrome ... diagnosis #causes #nephrology ... #sodium #low
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
), CK+LDH (lysis ... Elimination (see Table ... ) • Low K diet ... Slow - don’t delay ... Treatment #potassium #nephrology
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