19 results
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
mOsm/kg - Implies renal ... • Euvolemic (Low ... , Ingestion Renal ... , Cushing syndrome ... Algorithm #nephrology #sodium
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Epithelial Cells Renal ... cell epithelial sodium ... of epithelial sodium ... tubular acidosis ... #Differential #Table
Volume Based Approach to Hyponatremia
Hypovolemic, Serum uric acid >4
 • Urine Na <20: Extra-renal losses
 •
Based Approach to Hyponatremia ... Hypothyroidism, Low ... Cirrhosis, Nephrotic syndrome ... algorithm #diagnosis #sodium ... #low #nephrology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
Sodium loss (diuretics ... can be high or low ... Cirrhosis, Nephrotic syndrome ... differential #diagnosis #table ... #sodium #nephrology
Etiologies of Hypernatremia - Differential Diagnosis
GI losses / Insensible losses
Sodium Overload
Transcellular Movement of Water
Central Diabetes Insipidus
Etiologies of Hypernatremia ... Insensible losses Sodium ... hypokalemia - Various renal ... diseases (e.g. renal ... Differential #Diagnosis #Table
Hypernatremia Classification and Features According to Volume Status
 - Hypervolemic hypernatremia - Cushing's syndrome, Primary hyperaldosteronism,
Hypernatremia Classification ... - Cushing's syndrome ... Gestational DI, Nephrogenic ... Hypodipsia - Renal ... Diagnosis #Comparison #Table
Hyponatremia - Differential Diagnosis by Mechanism
Decr Blood Pressure (“Decr Effective Circulating Volume”) 
 - Volume depletion
Hyponatremia - Differential ... - Cirrhosis Syndrome ... Suppressed - Advanced renal ... Differential #Diagnosis #Table ... #Causes #Sodium
Distal Renal Tubular Acidosis
Distal RTA is the true Nephrogenic RTA and can be truly divided into
Distal Renal Tubular ... Acidosis Distal ... RTA is the true Nephrogenic ... intercalated cells - A Low ... diseases(Sjogren's Syndrome
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
asymptomatic to seizures ... in renal failure ... stimulated in states of low ... activated in states of low ... in the renal tubules
Lactic Acidosis - Differential Diagnosis Framework

Type A: Impaired O2 Delivery (DO2)
 • Decreased O2 Delivery: Hypotension
Ischemia, Compartment Syndrome ... Hypothermia & Shivering, Seizures ... toxic alcohols, Sodium ... liver Failure, Renal ... in Short Bowel Syndrome