26 results
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis ... • Euvolemic (Low ... , Cushing syndrome ... Workup #Algorithm #nephrology ... #sodium
Clinical manifestations of acute liver failure 

Brain: 
Hepatic encephalopathy,  
Cerebral edema,  
Intracranial hypertension,
hypertension, Seizures ... Coagulopathy, Lactic acidosis ... Subclinical myocardial injury ... lung injury, ... Signs #Symptoms #Diagnosis
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
Modified Hyponatremia ... Cirrhosis, Nephrotic syndrome ... Primary polydipsia, Low ... #Algorithm #diagnosis ... #sodium #nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... - Differential Diagnosis ... Abdominal Compartment Syndrome ... Nephrolithiasis) • Neurogenic ... #nephrology #causes
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
Acute Kidney Injury ... obstruction) • Neurogenic ... #Kidney #Injury ... Classification #diagnosis ... #nephrology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
cell epithelial sodium ... of epithelial sodium ... renal tubular acidosis ... Defects #Kidney #Nephrology ... #Diagnosis #Differential
Volume Based Approach to Hyponatremia
Hypovolemic, Serum uric acid >4
 • Urine Na <20: Extra-renal losses
 •
Based Approach to Hyponatremia ... Hypothyroidism, Low ... Cirrhosis, Nephrotic syndrome ... #algorithm #diagnosis ... #sodium #low #nephrology
Causes of Seizures - Differential Diagnosis Algorithm
Unprovoked - Epilepsy:
 • Focal: Simple, Complex
 • Generalized: Absence,
Causes of Seizures ... - Differential Diagnosis ... vasoconstriction syndrome ... Traumatic brain injury ... Hyperglycemia, Hyponatremia
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Causes of Hyponatremia ... - Differential Diagnosis ... with renal tubal acidosis ... UNa > 20: • Acute ... Algorithm #Causes #nephrology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
can be high or low ... Cirrhosis, Nephrotic syndrome ... #differential #diagnosis ... #table #sodium ... #nephrology