36 results
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
insipidus (central or nephrogenic ... Hypervolemic: Conn syndrome ... , Cushing syndrome ... Workup #Algorithm #nephrology ... #sodium
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Causes of Hypernatremia ... insipidus • Nephrogenic ... administration #Hypernatremia ... Diagnosis #Causes #nephrology ... #sodium #high
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Hypernatremia Diagnosis ... Repeat the sodium ... mmol/L - true hyponatremia ... • nephrotic syndrome ... Workup #Algorithm #Nephrology
Rate of Correction of Hypernatremia and Health Outcomes in Critically Ill Patients

CJASN May 2019, 14 (5)
Correction of Hypernatremia ... for mortality, seizure ... and/or cerebral edema ... #Hypernatremia # ... Correction #EBM #Nephrology
Rate of Correction of Hypernatremia and Health Outcomes in Critically Ill Patients

CJASN May 2019, 14 (5)
Correction of Hypernatremia ... correction of hypernatremia ... for mortality, seizure ... and/or cerebral edema ... Rate #Correction #Nephrology
Hypernatremia - Differential Diagnosis and Treatment
Hypernatremia is almost always due to unreplaced water loss (free water
Diabetes Insipidus: neurogenic ... , nephrogenic 4 ... risk for cerebral edema ... Treatment #management #nephrology ... #sodium
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Wasting vs SIADH - Pathophysiology ... Neurological event 2) Sodium ... SaltWasting #SIADH #Pathophysiology ... #diagnosis #nephrology ... #hyponatremia #
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
Modified Hyponatremia ... Algorithm Hypertonic Hyponatremia ... Cirrhosis, Nephrotic syndrome ... Algorithm #diagnosis #sodium ... #nephrology
Hypernatremia Classification and Features According to Volume Status
 - Hypervolemic hypernatremia - Cushing's syndrome, Primary hyperaldosteronism,
Hypernatremia Classification ... - Hypervolemic hypernatremia ... - Cushing's syndrome ... Gestational DI, Nephrogenic ... Comparison #Table #Nephrology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
cell epithelial sodium ... of epithelial sodium ... exchanger,H+-ATPase Nephrogenic ... -2 deficiency Nephrogenic ... Defects #Kidney #Nephrology