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Peripheral Neuropathy - Diagnostic Schema and Differential Diagnosis

Hereditary
Common Causes
Rapid Onset
Subacute/Chronic Onset
 - Multifocal
 - Focal
 -
Peripheral Neuropathy ... Hereditary Common Causes ... #Peripheral #Neuropathy ... #Differential # ... #neurology
Mechanisms of Pain
Mixed - Nociceptive/Neuropathic
Nociceptive - Tissue Damage
 - Visceral - (From organ/cavity lining) Poorly localized,
- Nociceptive/Neuropathic ... longer duration Neuropathic ... Pain #Mechanisms #Neurology ... #Differential # ... Diagnosis #Algorithm #Causes
Isocoria - Pupillary Defects - Differential Diagnosis Algorithm
Relative Afferent Pupil Defect
 • Optic Neuritis
 • Ischemic
Pupillary Defects - Differential ... Ischemic Optic Neuropathies ... Compressive Optic Neuropathy ... • Botulism Pharmacologic ... Diagnosis #Algorithm #Causes
Causes of Dizziness / Lightheadedness - Differential Diagnosis Algorithm
Lightheaded, unsteady, disoriented - Non-vertigo
Organic Disease
 • Presyncope/Vasodepressor
Causes of Dizziness ... Lightheadedness - Differential ... • Peripheral neuropathy ... Lightheadedness #Neurology ... #Differential #
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Causes of Peripheral ... Sensory Changes - Differential ... Neuron and Motor Neuropathy ... Peripheral #Weakness #Neurology ... #Differential #
Causes of Peripheral Weakness - With and Without Sensory Changes - Differential Diagnosis Algorithm
With Sensory Changes:
Causes of Peripheral ... Sensory Changes - Differential ... Neuron and Motor Neuropathy ... Weakness #Sensory #Neurology ... #Differential #
Multiple Cranial Neuropathies - High Yield Differential Diagnosis
 • Intrinsic brainstem process
 • Compressive brainstem process
Multiple Cranial Neuropathies ... - High Yield Differential ... rarely botulism) Casey ... #Differential # ... Diagnosis #causes
Transient Monocular Vision loss - Differential Diagnosis
Ischemia	
 - Large artery disease (atherothrombosis, embolus, dissection).
  -
Vision loss - Differential ... ischemic optic neuropathy ... Caused by decreased ... Ocular causes - ... Monocular #VisionLoss #Differential
Drugs and Classes Associated with DILI and Type of Liver Injury

#Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
Drugs and Classes ... #Medications #Differential ... LiverInjury #Hepatology #Pharmacology ... #Causes #DILI
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
of Peripheral Neuropathy ... #Peripheral #Neuropathy ... #differential # ... diagnosis #causes ... #neurology