11 results
Immune Checkpoint Inhibitor Toxicity

Main Toxicities: Colitis,  
Pneumonitis, Skin adverse events, Endocrine dysfunction, 
Hepatitis,  
Myocarditis,
Inhibitor Toxicity ... Incidence, Symptoms ... #Toxicities #SideEffects ... #Table #Diagnosis ... #Pharmacology #
Amiodarone Toxicity and Monitoring

Tremor Ataxia 
Ocular neuritis 
Corneal Microdeposits 
Bradycardia 
Pulmonary fibrosis 
Hepatotoxicity 
Blue-gray skin
Hypothyroid Peripheral Neuropathy ... Substrate CYP3A4 - Inhibitor ... #Monitoring #SideEffects ... #Adverse #Diagnosis ... #Management #Pharmacology
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Serotonin Reuptake Inhibitors ... Pathophysiology #Pharmacology ... #SideEffects #Psychiatry ... #Diagnosis #Signs ... #Symptoms
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Serotonin-Norepinephrine Reuptake Inhibitors ... Pathophysiology #Pharmacology ... #SideEffects #Psychiatry ... #Diagnosis #Signs ... #Symptoms
Risk Factors and Signs of Copper Deficiency
Risk Factors:
 • Gastrointestinal: Previous upper bowel resection/bariatric surgery, Inflammatory
Medications: Proton pump inhibitor ... Myelopathy, Peripheral neuropathy ... , Optic neuropathy ... #Deficiency #diagnosis ... #symptoms #nutrition
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
have preceding upper ... necrosis factor a inhibitors ... cell-mediated immune ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
cells are the immune ... of UMN and LMN signs ... body segment: Upper ... fasciculations Common Symptoms ... Riluzole - An inhibitor
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... activity → local immune ... seizure, cranial neuropathy ... anterior/posterior MSK ... #Management #Signs
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... Necrotizing, pauci-immune ... respiratory tracts Immune ... Presentation - Systemic Symptoms ... purpura: strong sign
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... Sensory and/or motor neuropathy ... weakness • Nerves: Neuropathy ... • Progressive symptoms