6305 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
inflammation: Increased neutrophils ... Differential Diaqnoses ... hepatitis • Pulmonary ... Stills #Disease #diagnosis
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
hit mechanism of neutrophil ... , and CXR with pulmonary ... Reactions #hematology #diagnosis
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm
Infection
 • Bacterial
 • Abscess
 • Viral
Medications
Causes of Neutrophilia ... - Increased Neutrophils ... - Differential Diagnosis ... #Increased #Neutrophils ... #Differential #Diagnosis
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
Hypersegmented neutrophil ... Dysplastic neutrophils ... Hypersegmented #neutrophils
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
acute febrile neutrophilic ... dermatosis Diagnosis ... Imaging: CXR- pulmonary ... opacities • Diagnosis ... • Differential Diagnosis
How to distinguish a metamyelocyte from a band neutrophil.

- Kyle Bradley, MD
@KyleBradleyMD

#Clinical #Pathology #Microscopy #Blood #Smear
metamyelocyte from a band neutrophil ... Metamyelocytes #Bands #Neutrophils
Sweet’s Syndrome - Acute febrile neutrophilic dermatosis 

The syndrome involves fever, painful rash, neutrophilic leukocytosis, and
Acute febrile neutrophilic ... painful rash, neutrophilic ... leukocytosis, and neutrophil ... Sweets #Syndrome #neutrophilic
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
pneumonitis Diagnosis ... pneumonia - Pulmonary ... suggestive but not diagnostic ... Lymphocytosis • Neutrophilia ... #diagnosis #management
Evaluation of Leukocytosis:
The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages.
Include
granulocytes (neutrophils ... Neutrophil bands ... : Immature neutrophils ... as significant neutrophilia ... Mature neutrophils
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
> 10% Band neutrophils ... Band neutrophils ... Differential Diagnosis ... counts may delay diagnosis ... #differential #diagnosis